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Lyme Times
Winter 2014 Issue
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LymeTimes Winter 2014 Issue
Evidence-Based Medicine

Knowing where evidence ends and values begin is important to patients with Lyme disease.

By Lorraine Johnson, JD, MBA

3
State of the Science

LLMD presents his “Top-Ten List” of Lyme facts uncovered over the last 25 years

By Raphael Stricker, MD

5
NIH Clicnical Trials

What we learned from four famous trials funded by the National Institutes of Health Brian Fallon, MD, MPH

By Brian Fallon, MD, MPH

6
Understanding Persistence

Columbia University research center pursues a cure for chronic Lyme

By Brian Fallon, MD, MPH

7
Chronic Lyme Disease Clinical Trails

Clarifying the benefits of amoxicillin

By Dan Cameron, MD, MPH

9
Embers at a Glance

Monkey study confirms post-treatment infection

By Lorraine Johnson, JD, MBA

11
Evidence of Lyme Disease Persistence

Worldwide studies confirm persistent infection

By Raphael Striker, MD & Lorraine Johnson, JD, MBA

12
Embers vs. the IDSA Study

Contradicts IDSA opinion on tests, treatment and persistence

By Lorraine Johnson, JD, MBA

13
ILADS Treatment Guidelines Revised

Trustworthy treatment guidelines must reflect available science, clinical judgment and patient values

By Dan Cameron, MD, MPH; Betty Maloney, MD; & Lorraine Johnson, JD, MBA

14
ILADS 2014 Conference

As the ILADS membership grows, increasing numbers of practitioners benefit from a sea of emerging knowledge

By Pamela Cocks, MPH, MLS

24
Xenodiagnosis

Ticks detect persistent infection in post-treatment patients

By Betty Maloney, MD

25
Borrelia Biofilms

A Complex slime renders Bb resistant to antibiotics

By Eva Sapi, PhD, & David Luecke, MA

28
The Complications of Co-infections

Blood-sucking parasites transmit a world of disease into the lives of Lyme patients

By Lorraine Johnson, JD, MBA

30
Tick-Borne Disease Epidemiology

California ticks carry a plethora of disease agents to unsuspecting Lyme patients

By Robert S. Lane, PhD

31
Where are the Studies?

Pathology studies must focus on patients with relapsing symptoms

By Tom Grier

32
Lyme Neuropathology

Pathologist identifies Bb spirochete in Alzheimer’s brain tissue

By Alan B. McDonald, MD

33
Patient-Powered Research

How patient involvement in research design can improve care for Lyme disease patients.

By Lorraine Johnson, JD, MBA

36

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